Spermidine
Spermidine is a naturally occurring polyamine that induces autophagy—your body's cellular cleanup process. It's found in aged cheese, wheat germ, and other foods, and is emerging as a longevity supplement.
Research Level: Promising but limited human data
Dosage
1-6mg daily; higher doses in studies
When to Take
Can be taken any time. Some prefer morning.
Benefits
- ✓Induces autophagy (cellular cleanup)
- ✓May slow aging processes
- ✓Supports cardiovascular health
- ✓May improve cognitive function
- ✓Supports healthy hair growth
- ✓May enhance immune function
How It Works
Spermidine triggers autophagy, the process by which cells break down and recycle damaged components. This 'cellular housekeeping' is crucial for healthy aging and declines as we age.
Food Sources
Possible Side Effects
- •Generally well-tolerated
- •Possible GI upset
- •Limited human safety data at high doses
Drug Interactions
- •Theoretically may interact with autophagy-modulating drugs
- •Limited interaction data available
What to Look For
- →Wheat germ extract (natural source)
- →Standardized spermidine content
- →Third-party tested
Medical Disclaimer
This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before starting any supplement, especially if you have existing health conditions or take medications. Supplements are not FDA-approved to diagnose, treat, cure, or prevent any disease.